Due to activity restrictions
Increased concentration of adrenal gland hormones. The first symptoms of this disorder appear after birth and are visible in external reproductive organs, rapid growth, early puberty. Later there is a high incidence of hypertension and obesity due to high levels of steroids.
Leptin is a hormone reducing the sensation of appetite. Usually, the concentration of this substance increases after meals and inhibits appetite center in the central nervous system. The symptoms of leptin deficiency include excessive eating, obesity, high concentrations of insulin and increased susceptibility to infections.